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Dib u eegis dhowaan ay daabacday koox cilmi baaris cilmiyeed oo Canadian ah ayaa soo jeedinaysa in cannabinoids laga yaabo inay door ka ciyaaraan ka hortagga iyo daawaynta COVID-19 iyo COVID-muda dheer.

Dib u eegis dhamaystiran, koox saynisyahano Canadian ah ayaa bixiya aragtiyo xiiso leh oo ku saabsan doorka suurtagalka ah ee cannabinoids ee la dagaallanka fayraska COVID-19.Daraasadda, oo cinwaan looga dhigay "Cannabinoids iyo Nidaamka Endocannabinoid ee Hore ee SARS-CoV-2 iyo Bukaannada Chronic COVID-19," waxaa qoray Cassidy Scott, Stefan Hall, Juan Zhou, Christian Lehmann iyo kuwa kale waxaana lagu daabacay Joornaalka SARS-CoV -2 ″ joornaal.

Daawooyinka Caafimaadka.Iyadoo la falanqeynayo xogta ballaaran ee daraasadihii hore, warbixintu waxay ka hadlaysaa sida qaybaha geedka xashiishadda ay door muhiim ah uga ciyaari karaan ka hortagga bilawga COVID-19 iyo yaraynta saameyntiisa mustaqbalka fog.Natiijooyinku waxay soo jeedinayaan in cannabinoids, gaar ahaan kuwa laga soo saaro geedka xashiishadda, ay joojin karaan gelitaanka fayraska ee unugyada, yaraynta cadaadiska oksaydhka ee waxyeellada leh, iyo in la xakameeyo jawaabta difaaca ee inta badan dilaa ah ee lagu arko xaaladaha daran.Daraasadu waxay sidoo kale muujineysaa doorka suurtagalka ah ee cannabinoids ee wax ka qabashada calaamadaha kala duwan ee socda ee COVID-19 muddada-dheer.

Sida laga soo xigtay daraasadda, cannabinoids waxay leeyihiin awood ay uga hortagaan gelitaanka fayraska, yaraynta cadaadiska oksaydhka iyo yaraynta duufaanka cytokine ee la xidhiidha fayraska COVID-19.Cilmi-baaristu waxay muujinaysaa in gaar ahsoosaarayaasha cannabinoidwaxay hoos u dhigi kartaa heerarka angiotensin-converting enzyme 2 (ACE2) ee unugyada muhiimka ah, taas oo ka hortagaysa fayrasyada inay galaan unugyada aadanaha.Cilmi-baarayaashu waxay xuseen in tani ay tahay mid muhiim ah marka la eego doorka ACE2 oo ah albaabka koowaad ee gelitaanka fayraska.Warbixintu waxay sidoo kale ka hadlaysaa doorka cannabinoids ee wax ka qabashada diiqada oksaydhka, oo ah arrin muhiim ah oo ka mid ah cudurrada faafa ee COVID-19.

Adiga oo u beddelaya xagjiriinta xorta ah qaabab falcelis yar, cannabinoids sidaCBDwaxay kaa caawin kartaa yaraynta waxyeelada waxyeelada leh ee diiqada oksaydhka xaaladaha daran ee COVID-19.Sida laga soo xigtay daraasadda, cannabinoids ayaa sidoo kale laga yaabaa inay saameyn faa'iido leh ku yeeshaan duufaannada cytokine, jawaabta difaaca daran ee uu kiciyay COVID-19.Cannabinoids ayaa la muujiyay inay wax ku ool u yihiin dhimista cytokines bararka, iyagoo soo jeedinaya kartidooda maaraynta jawaabaha difaaca jirka.

COVID-dheer waxaa loola jeedaa xaaladda sida caadiga ah dhacda marka COVID-19 uu u gudbo marxaladda dabadheeraatay.Cilmi-baaristu waxay daaha ka qaadaysaa awoodda cannabinoids ee daaweynta calaamadaha joogtada ah ee niyad-jabka, walaaca, khalkhalka post-traumatic stress, hurdo la'aan, xanuunka iyo rabitaanka cuntada oo luma.Nidaamka endocannabinoid wuxuu door ka ciyaaraa isdhexgalka hababka dareemayaasha ee kala duwan, taas oo ka dhigaysa bartilmaameedka daaweynta calaamadahan neuropsychiatric.

Daraasadu waxay sidoo kale sahamisay hababka kala duwan ee isticmaalka iyo noocyada kala duwan ee alaabta xashiishadda ee ay isticmaalaan macaamiisha.Cilmi-baaristu waxay muujinaysaa in la neefsashada neefsashada ay saameyn xun ku yeelan karto dadka qaba xaaladaha neef-mareenka, iyada oo ka hortagaysa saameynteeda daweynta."In kasta oo sigaar cabista iyo vaping-ka ay inta badan yihiin hababka la doorbido bukaannada xashiishadda sababtoo ah waxay leeyihiin bilawga ugu dhaqsaha badan, faa'iidooyinka suurtagalka ah ee daawaynta cannabinoid waxaa laga yaabaa inay ka soo baxaan saameynta xun ee neefsashada ee caafimaadka neefsashada," cilmi-baarayaashu waxay yiraahdeen.Daraasadu waxay muujinaysaa "Bukaannada isticmaala uumiga xashiishadda waxay la kulmaan calaamado yar oo neefsasho ah marka loo eego sigaarka sababtoo ah qalabka uumiga ma kululeeyo xashiishadda ilaa heer gubasho."Qorayaasha warbixinta ayaa carrabka ku adkeeyay baahida loo qabo cilmi-baaris dheeraad ah oo ku saabsan aaggan.In kasta oo natiijooyinka hordhaca ah ay dhiirigelinayaan, waxay ka digayaan inay hordhac yihiin oo ay ka soo jeedaan daraasado aan gaar u ahayn COVID-19.Sidaa darteed, daraasado badan oo la beegsaday oo dhamaystiran, oo ay ku jiraan tijaabooyin caafimaad, ayaa muhiim u ah in si buuxda loo fahmo doorka iyo waxtarka cannabinoids ee daawaynta goor hore iyo wejiga degdega ah ee SARS-CoV-2.Intaa waxaa dheer, qorayaashu waxay u doodayaan cilmi-baaris qoto-dheer oo qoto-dheer oo ku saabsan farmashiyaha iyo codsiyada daweynta ee suurtogalka ah ee nidaamka endocannabinoid waxayna ku booriyaan bulshada sayniska inay si adag u sahamiyaan habkan.


Waqtiga boostada: Jan-17-2024